The pharmaceutical world was shaken up in May 2014 as Allergan, the manufacturer of the best-selling synthetic neurotoxin Botox®, drew a merger bid of nearly $50 billion from rival pharmaceutical giant Valeant. At the time the bid was tendered, Allergan was also celebrating the 25th anniversary of Botox®, which has been credited with being one of the factors that inspired the development of surgery as a viable option for qualified patients who suffer from chronic migraines.